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Single-Arm Phase II Survival Trial Design

List Price: $67.99
SKU:
9780367653491
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  • Product Details

    Author:
    Jianrong Wu
    Format:
    Paperback
    Pages:
    273
    Publisher:
    CRC Press (July 24, 2023)
    Language:
    English
    ISBN-13:
    9780367653491
    Weight:
    15.625oz
    Dimensions:
    6.125" x 9.1875"
    File:
    TAYLORFRANCIS-TayFran_260513043736269-20260513.xml
    Folder:
    TAYLORFRANCIS
    List Price:
    $67.99
    Series:
    Chapman & Hall/CRC Biostatistics Series
    As low as:
    $64.59
    Publisher Identifier:
    P-CRC
    Discount Code:
    H
    Country of Origin:
    United States
    Pub Discount:
    30
    Imprint:
    Chapman and Hall/CRC
    Case Pack:
    1
  • Overview

    Single-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints. Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, particular for target therapy and immunotherapy in which time-to-event endpoints are often the primary endpoints. Most test statistics for single-arm phase II trial design with time-to-event endpoints are not available in commercial software.

    Key Features:

    • Covers the most frequently used methods for single-arm phase II trial design with time-to-event endpoints in a comprehensive fashion.
    • Provides new material on phase II immunotherapy trial design and phase II trial design with TTP ratio endpoint.
    • Illustrates trial designs by real clinical trial examples
    • Includes R code for all methods proposed in the book, enabling straightforward sample size calculation.