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Meta-analysis of Binary Data Using Profile Likelihood

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9780367387570
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  • Product Details

    Author:
    Dankmar Bohning, Sasivimol Rattanasiri, Ronny Kuhnert
    Format:
    Paperback
    Pages:
    208
    Publisher:
    CRC Press (October 21, 2019)
    Language:
    English
    ISBN-13:
    9780367387570
    Weight:
    16oz
    Dimensions:
    6.125" x 9.1875"
    File:
    TAYLORFRANCIS-TayFran_260122055321541-20260122.xml
    Folder:
    TAYLORFRANCIS
    List Price:
    $89.99
    Country of Origin:
    United States
    Series:
    Chapman & Hall/CRC Interdisciplinary Statistics
    As low as:
    $85.49
    Publisher Identifier:
    P-CRC
    Discount Code:
    H
    Pub Discount:
    30
    Imprint:
    Chapman and Hall/CRC
    Case Pack:
    1
  • Overview

    Illustrating the use of meta-analysis in many real-world trial examples, this work focuses on the analysis and modeling of a meta-analysis with individually pooled data (MAIPD). It explores alternatives to the profile likelihood method, including approximated likelihood and multilevel models, and shows how the nonparametric profile maximum likelihood estimator can be computed via the EM algorithm with a gradient function update. The authors explain how to test for and determine the amount of heterogeneity in an MAIPD. They also highlight the application of the software program CAMAP for analyzing an MAIPD and offer the software for free online.