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Handbook of Mitochondrial Dysfunction

List Price: $70.99
SKU:
9781032178004
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  • Product Details

    Author:
    Shamim I. Ahmad
    Format:
    Paperback
    Pages:
    504
    Publisher:
    CRC Press (September 30, 2021)
    Language:
    English
    ISBN-13:
    9781032178004
    Weight:
    32.875oz
    Dimensions:
    8.25" x 11"
    File:
    TAYLORFRANCIS-TayFran_260825154147485-20260825.xml
    Folder:
    TAYLORFRANCIS
    List Price:
    $70.99
    Case Pack:
    1
    As low as:
    $67.44
    Publisher Identifier:
    P-CRC
    Discount Code:
    H
    Country of Origin:
    United States
    Pub Discount:
    30
    Imprint:
    CRC Press
  • Overview

    Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book.





    Key Features







    • Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction.






    • Includes summary of both causes and effects of these diseases.






    • Discusses current and potential future therapies for mitochondrial dysfunction diseases






    • Explores a wide variety of diseases caused by dysfunctional mitochondria.