An Introduction to Toxicogenomics

Gathering together leading authors and scientists at the forefront of the field, An Introduction to Toxicogenomics provides a comprehensive overview of this emerging subdiscipline. The book introduces the overall concept underlying microarray/oligonucleotide array-based genomic analysis and how it fits into the field of biomedical research. These discussions provide an overview of the actual mechanics of the analyses themselves and offer insights on handling and quality control. An important feature is the book's focus on the basics of data analysis and clustering methods, such as genetic algorithms, used for analyzing large-scale datasets derived from gene chip expression data.